PPAR-γ Agonism for Cardiovascular and Renal Protection
نویسندگان
چکیده
منابع مشابه
Dual PPAR α/γ Agonism Normalizes Lipoprotein Profile of Renal Dyslipidemia
Chronic kidney disease (CKD) is characterised by specific lipoprotein abnormalities and insulin resistance. Dual activation of the peroxisome proliferators-activated receptors (PPAR) α and γ can significantly improve insulin sensitivity. The aim of the study was to investigate the effects of a dual PPAR α / γ agonist on lipoprotein abnormalities in patients with CKD. One mg of the dual PPAR α /...
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The role of peroxisome proliferator-activated receptors (PPARs) in altering lipid and glucose metabolism is well established. More recent studies indicate that PPARs also play critical roles in controlling immune responses. We and others have previously demonstrated that PPAR-gamma agonists modulate the development of experimental autoimmune encephalomyelitis (EAE), an animal model of multiple ...
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ژورنال
عنوان ژورنال: Cardiovascular Therapeutics
سال: 2010
ISSN: 1755-5914
DOI: 10.1111/j.1755-5922.2010.00222.x